Isolation and structural determination of makinolide B from Streptomyces sp. MK-19.
نویسندگان
چکیده
A new 16-membered macrolide named makinolide B (1) was isolated from Streptomyces sp. MK-19. The structure of makinolide B (1) was determined on the basis of 2D NMR experiments involving DQF-COSY, TOCSY, HSQC, and HMBC methods. Application of the paper disk diffusion method to makinolide B (1) showed weak antibacterial activity against Staphylococcus aureus at the dose of 100 µg/disk.
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ورودعنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 77 9 شماره
صفحات -
تاریخ انتشار 2013